Annually repeated influenza vaccination improves humoral responses to several influenza virus strains in healthy elderly

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Annually repeated influenza vaccination improves humoral responses to several influenza virus strains in healthy elderly.

The benefit of annually repeated influenza vaccination on antibody formation is still under debate. In this study the effect of annually repeated influenza vaccination on haemagglutination inhibiting (HI) antibody formation in the elderly is investigated. Between 1990 and 1993 healthy young and elderly, both selected by the SENIEUR protocol, were vaccinated consecutively with commercially avail...

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Protection against influenza after annually repeated vaccination: a meta-analysis of serologic and field studies.

BACKGROUND According to common recommendations, influenza vaccination should be performed annually. It has been suggested that vaccination in previous years reduces vaccine efficacy in the long term. OBJECTIVE To determine whether the protection of influenza vaccine decreases when vaccination is repeated annually. METHODS Articles published between 1966 and 1997 were selected from MEDLINE. ...

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Variable efficacy of repeated annual influenza vaccination.

Conclusions have differed in studies that have compared vaccine efficacy in groups receiving influenza vaccine for the first time to efficacy in groups vaccinated more than once. For example, the Hoskins study [Hoskins, T. W., Davis, J. R., Smith, A. J., Miller, C. L. & Allchin, A. (1979) Lancet i, 33-35] concluded that repeat vaccination was not protective in the long term, whereas the Keitel ...

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ژورنال

عنوان ژورنال: Vaccine

سال: 1997

ISSN: 0264-410X

DOI: 10.1016/s0264-410x(97)00019-4